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Treatment of short stature with certain
inhibitors will delay bone maturation and increase height.

By Michael Burke

Body Image Solutions

Researchers are currently using a potent P450-aromatase inhibitor, letrozole, because of its ability to delay bone maturation and increase final adult height.

Estrogen plays an essential role in the regulation of bone maturation and ultimately causes bones to fuse resulting in increased adult height.

Studies have proven and shown that letrozole is the key inhibitor in stopping estrogen from causing bone maturation.

As a result, young adults who were given letrozole reached an average increased final adult height of 5.1 cm (2 inches) during the five month treatment which is remarkable considering the fact that they did not have to do anything for the additional height.

Had these same individuals undergone a strict anaerobic stretching exercise program which has been proven to increase human growth hormone levels substantially they would have gained an average of four-five inches instead of two.

The inhibition of estrogen synthesis delayed bone
maturation. These findings indicates that an increase in adult height can be attained in growing adolescent boys or even adults who have open growth plates
by inhibiting of estrogen action.

Therefore, the pubertal growth rate of young adults can be blocked thereby preventing bone maturation and increasing final height prognosis.~*

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