Nutrition

Treatment
of short stature with certain
inhibitors will delay bone maturation and increase
height.
By Michael Burke
Body Image Solutions
Researchers
are currently using a potent P450-aromatase inhibitor, letrozole, because of its
ability to delay bone maturation and increase final adult height.
Estrogen
plays an essential role in the regulation of bone maturation and ultimately causes
bones to fuse resulting in increased adult height.
Studies
have proven and shown that letrozole is the key inhibitor in stopping estrogen
from causing bone maturation.
As
a result, young adults who were given letrozole reached an average increased final
adult height of 5.1 cm (2 inches) during the five month treatment which is remarkable
considering the fact that they did not have to do anything for the additional
height.
Had these
same individuals undergone a strict anaerobic stretching exercise program which
has been proven to increase human growth hormone levels substantially they would
have gained an average of four-five inches instead of two.
The
inhibition of estrogen synthesis delayed bone
maturation. These findings indicates
that an increase in adult height can be attained in growing adolescent boys or
even adults who have open growth plates
by inhibiting of estrogen action.
Therefore,
the pubertal growth rate of young adults can be blocked thereby preventing bone
maturation and increasing final height prognosis.~*
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